📣 Publications & Patents

Publications

Below is a condensed selection of peer-reviewed work and intellectual property related to translational bioinformatics, MRD detection, and long-read sequencing. Image slots and [[Link]] references mirror the original layout so you can easily swap in updated figures.

Shu, T., Liang, Y., Zhang, S., et al. (2024). The prognostic value of tumor-informed minimal residual disease detection using circulating tumor DNA in first-line treatment of ovarian cancer. Gynecologic Oncology. [Link]

Geng, C.†, Tong, Y.†, Zhang, S., et al. (2021). Sequence and structure characteristics of 22 deletion breakpoints in intron 44 of the DMD gene based on long-read sequencing. Frontiers in Genetics, 12, 638220. [Link]

Jiang, Y., Wu, L., Huang, S., Li, P., Gao, B., Yuan, Y., Zhang, S., et al. (2021). Study of complex structural variations of X-linked deafness-2 based on single-molecule sequencing. Bioscience Reports, 41(6), BSR20203740. [Link]

Xie, Z., Sun, C., Zhang, S., et al. (2020). Long-read whole-genome sequencing for the genetic diagnosis of dystrophinopathies. Annals of Clinical and Translational Neurology, 7(10), 2041–2046. [Link]

Jiang, Z., Liu, H., Zhang, S., et al. (2020). A novel method for microsatellite instability detection by liquid biopsy based on next-generation sequencing. Current Bioinformatics, 15(1). [Link]

Xu, H.†, Wu, X.†, Sun, D.†, Li, S.†, Zhang, S.†, et al. (2018). SEGF: A novel method for gene fusion detection from single-end next-generation sequencing data. Genes, 9(7), 331. [Link]

† These authors contributed equally.

Patents

• CN112593015B (2023) — Liquid-biopsy–based MRD and MSI analytics for gynecological oncology.
• CN108304693B (2022) — Methods and systems for highly accurate detection of genomic alterations in oncology samples.
• CN108949757B (2021) — Targeted amplification workflow improvements for structural variation profiling via third-generation sequencing.